Article
The circadian clock mutation alters sleep homeostasis in the mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Nov 2000
Naylor E, Bergmann B M, Krauski K, Zee P C, Takahashi J S, Vitaterna M H, Turek F W
Abstract excerpt
The onset and duration of sleep are thought to be primarily under the control of a homeostatic mechanism affected by previous periods of wake and sleep and a circadian timing mechanism that partitions wake and sleep into different portions of the day and night. The mouse Clock mutation induces pr...
Topics
- Animals
- Behavior, Animal
- Biological Clocks
- Circadian Rhythm
- Electroencephalography
- Heterozygote
- Homeostasis
- Homozygote
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Neurologic Mutants
- Mutation
- Sleep
- Sleep Deprivation
- Sleep Stages
- Wakefulness