Article
Genotyping for human whole-genome scans: past, present, and future.
Advances in genetics - 1 Jan 2001
Weber J L, Broman K W
Abstract excerpt
Efficient and effective whole-genome 10-cM short tandem repeat polymorphism (STRP) scans are now available. Doubling or tripling STRP density to an average spacing of 3-5 cM is readily achievable. However, if typing costs for diallelic polymorphisms can be brought close to, or preferably less than, one-third those of STRPs, then diallelics may gradually supplement or supplant STRPs in whole-genome scans. The...
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