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Article

X-linked agammaglobulinaemia and the underlying genetics in two kindreds.

Journal of paediatrics and child health - 1 Oct 2000

Pienaar S, Eley B, Beatty D W, Henderson H E

Abstract excerpt

OBJECTIVE: Molecular analysis of the Bruton's tyrosine kinase (Btk) gene in two unrelated families, with a combined total of seven boys, affected by X-linked agammaglobulinaemia (XLA). METHODS: Protein electrophoresis and western blotting were used for the examination of Btk protein synthesis in blood leucocytes. Isolation of the coding sequence of the Btk gene was performed by amplification using the reverse...

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Source

Identifiers

PMID: 11036800
DOI: 10.1046/j.1440-1754.2000.00546.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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