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Article

Escort aptamers: a delivery service for diagnosis and therapy

15 Oct 2000

Abstract excerpt

In 1990, the discovery of aptamers by Tuerk and Gold (1) and subsequently by Ellington and Szostak (2) spawned significant interest within academia and industry. Aptamers have quickly become valuable research tools (3-5). More than that, a therapeutic aptamer (6) has entered clinical evaluation just eight years after the inception of the technology. While aptamers have built inroads into therapeutic applications,...

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PMID: 11032850
DOI: 10.1172/jci11324

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