Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutants of a temperature-sensitive two-P domain potassium channel.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Oct 2000

Kunkel M T, Johnstone D B, Thomas J H, Salkoff L

Abstract excerpt

Within the Caenorhabditis elegans genome there exist at least 42 genes encoding TWK (two-P domain K(+)) channels, potassium channel subunits that contain two pore regions and four transmembrane domains. We now report the first functional characterization of a TWK channel from C. elegans. Although potassium channels have been reported to be activated by a variety of factors, TWK-18 currents increase dramatically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Locomotion
Share to Luminescent Proteins
Share to Muscles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oocytes

Share to Patch-Clamp Techniques

Share to Potassium

Share to Potassium Channels

Share to Xenopus

Source

Open in PubMed Open full text

Identifiers

PMID: 11027209
PMCID: PMC6772866

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutants of a temperature-sensitive two-P domain potassium channel.PMID 11027209Read ↗

kin-18, a C. elegans protein kinase involved in feeding.Semantic proximity Read ↗

Locomotion Behavior Is Affected by the GαS Pathway and the Two-Pore-Domain K+ Channel TWK-7 Interacting in GABAergic Motor Neurons in Caenorhabditis elegans.Semantic proximity Read ↗

Complex Locomotion Behavior Changes Are Induced in Caenorhabditis elegans by the Lack of the Regulatory Leak K+ Channel TWK-7.Semantic proximity Read ↗

Developmental genetic analysis of troponin T mutations in striated and nonstriated muscle cells of Caenorhabditis elegans.Semantic proximity Read ↗

Functional validation of human SK channels variants causing NEDMAB and Zimmermann-Laband syndrome-3 in <i>C. elegans</i>Semantic proximity Read ↗

Behavioral defects in C. elegans egl-36 mutants result from potassium channels shifted in voltage-dependence of activation.Semantic proximity Read ↗

A survey of new temperature-sensitive, embryonic-lethal mutations in C. elegans: 24 alleles of thirteen genes.Semantic proximity Read ↗

The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size.Semantic proximity Read ↗

A small conductance calcium-activated K+ channel in C. elegans, KCNL-2, plays a role in the regulation of the rate of egg-laying.Semantic proximity Read ↗

An arrhythmia susceptibility gene in Caenorhabditis elegans.Semantic proximity Read ↗

KCNK18 c.1107del frameshift in peripheral neuropathy links TRESK dysfunction to neuropathic painSemantic proximity Read ↗

A mutation in the C. elegans EXP-2 potassium channel that alters feeding behavior.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.