Article
Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum.
Molecular biology and evolution - 1 Oct 2000
Anderson T J, Haubold B, Williams J T, Estrada-Franco J G, Richardson L, Mollinedo R, Bockarie M, Mokili J, Mharakurwa S, French N, Whitworth J, Velez I D, Brockman A H, Nosten F, Ferreira M U, Day K P
Abstract excerpt
Multilocus genotyping of microbial pathogens has revealed a range of population structures, with some bacteria showing extensive recombination and others showing almost complete clonality. The population structure of the protozoan parasite Plasmodium falciparum has been harder to evaluate, since most studies have used a limited number of antigen-encoding loci that are known to be under strong selection. We...
Topics
- Africa
- Animals
- Biological Evolution
- Evolution, Molecular
- Gene Frequency
- Genetic Variation
- Genotype
- Geography
- Humans
- Linkage Disequilibrium
- Malaria, Falciparum
- Microsatellite Repeats
- Papua New Guinea