Article
The channel-forming protein proaerolysin remains a dimer at low concentrations in solution.
The Journal of biological chemistry - 5 Jan 2001
Barry R, Moore S, Alonso A, Ausió J, Buckley J T
Abstract excerpt
Proaerolysin, the proform of the channel-forming protein aerolysin, is secreted as a dimer by Aeromonas sp. The protein also exists as a dimer in the crystal, as well as in solution, at least at concentrations in the region of 500 microg/ml. Recently it has been argued that proaerolysin becomes monomeric at concentrations below 100 microg/ml and that only the monomeric form of the protoxin can bind to cell...
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