Article
Cellular uptake and nuclear delivery of recombinant adenovirus penton base.
Virology - 15 Sept 1999
Hong S S, Gay B, Karayan L, Dabauvalle M C, Boulanger P
Abstract excerpt
An Ad2 capsid component, the penton base, expressed as recombinant protein, was found to be capable of affecting the entire entry pathway of adenovirion in HeLa cells, i.e., cell attachment, endocytosis, vesicular escape, intracytoplasmic movement, and translocation through the nuclear pore complex. Data with pentamerization-defective mutants suggested that none of these successive steps depended upon penton base...
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