Article
Treatment-related leukaemia--a clinical and scientific challenge.
Cancer treatment reviews - 1 Oct 2000
Ng A, Taylor G M, Eden O B
Abstract excerpt
The development of a second tumour, including treatment-related leukaemia (TRL), is the most devastating complication of intensive cancer chemotherapy. This is especially relevant in the paediatric population as over 70% of children diagnosed with a malignancy will now live at least 5 years. Most TRLs are myeloid leukaemias and carry an overall poor prognosis when compared with their de novo counterparts. Despite...
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