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Article

Familial sarcoidosis is linked to the major histocompatibility complex region.

American journal of respiratory and critical care medicine - 1 Sept 2000

Schürmann M, Lympany P A, Reichel P, Müller-Myhsok B, Wurm K, Schlaak M, Müller-Quernheim J, du Bois R M, Schwinger E

Abstract excerpt

Sarcoidosis is a systemic granulomatous disorder associated with high CD4+ cell activity, but no pathogen is detectable. Clustering in families occurs, and the existence of a genetic predisposition to sarcoidosis is widely accepted. The major histocompatibility complex (MHC) is believed to contribute to this susceptibility. Many studies testing this hypothesis have produced conflicting results. We have genotyped...

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Share to Chromosomes, Human, Pair 6
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10988096
DOI: 10.1164/ajrccm.162.3.9901099

Genes

NPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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