Article
Molecular genetics improves the management of hereditary non-polyposis colorectal cancer.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde - 1 Jul 2000
Ramesar R S, Madden M V, Felix R, Harocopos C J, Westbrook C A, Jones G, Cruse J P, Goldberg P A
Abstract excerpt
BACKGROUND: The syndrome of hereditary non-polyposis colorectal cancer (HNPCC) can be diagnosed fairly accurately using clinical criteria and a family history. Identifying HNPCC helps to prevent large-bowel cancer, or allows cancer to be treated at an early stage. Once the syndrome has been diagn...
Topics
- Adult
- Chromosomes, Human, Pair 3
- Colorectal Neoplasms, Hereditary Nonpolyposis
- DNA, Neoplasm
- Endoscopy, Gastrointestinal
- Female
- Genetic Counseling
- Genetic Testing
- Humans
- Male
- Molecular Biology