Article
Is it possible to differentiate mtDNA by means of HVIII in samples that cannot be distinguished by sequencing the HVI and HVII regions?
Forensic science international - 11 Sept 2000
Lutz S, Wittig H, Weisser H J, Heizmann J, Junge A, Dimo-Simonin N, Parson W, Edelmann J, Anslinger K, Jung S, Augustin C
Abstract excerpt
The mitochondrial control region includes three so-called hypervariable (HV) regions, in which the polymorphic positions show a particularly high frequency. According to a population study of 200 unrelated individuals from Germany, HVI (positions 16,024-16,365, according to Anderson) showed 88 variable positions in a total length of 342 bp (26%) and HVII (positions 73-340) displayed 65 mutable sites in 268 bp...
Topics
- Austria
- Complementarity Determining Regions
- DNA Fingerprinting
- DNA, Mitochondrial
- Databases, Factual
- Gene Frequency
- Genetic Variation
- Germany
- Humans
- Polymorphism, Genetic
- Sampling Studies
- Sequence Analysis, DNA
- Switzerland