Article
Redefinition of hypervariable region I in mitochondrial DNA control region and comparing its diversity among various ethnic groups.
Mitochondrion - 1 Mar 2008
Tzen Jessica M, Hsu Hsiu-Jun, Wang Man-Ning
Abstract excerpt
The hypervariable region I (HVR-I) of the mitochondrial DNA control region described in the literature is variable in its 5'and 3' ends as well as in its length, causing a problem when data from different ethnic groups are to be compared. To redefine HVR-I, which should be highly polymorphic yet relatively short in length, we analyzed 1437 reported sequences distributed among 11 geographic areas in the world. The...
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