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Article

The voltage gated potassium channel KCNQ2 and idiopathic generalized epilepsy.

Neuroreport - 26 Apr 1999

Steinlein O K, Stoodt J, Biervert C, Janz D, Sander T

Abstract excerpt

Mutations in the voltage gated potassium channel gene KCNQ2 and the homologous gene KCNQ3 have been found to cause a rare monogenic subtype of idiopathic generalized epilepsy, the benign familial neonatal convulsions. Recently, the heteromeric KCNQ2/KCNQ3 channel was found to contribute to the native M-current, one of the most important regulators of neuronal excitability. By performing a systematic mutation scan...

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Source

Identifiers

PMID: 10363917
DOI: 10.1097/00001756-199904260-00001

Genes

KCNQ2
KCNQ3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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