The R28 protein of <i>Streptococcus pyogenes</i> is related to several group B streptococcal surface proteins, confers protective immunity and promotes binding to human epithelial cells

Abstract excerpt

The R28 protein is a surface molecule expressed by some strains of Streptococcus pyogenes (group A streptococcus). Here, we present evidence that R28 may play an important role in virulence. Sequence analysis demonstrated that R28 has an extremely repetitive sequence and can be viewed as a chimera derived from the three surface proteins Rib, alpha and beta of the group B streptococcus (GBS). Thus, the gene...

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