System-theoretical (Holistic) approach to the modelling of structural-functional relationships of biomolecules and their evolution: an example of triterpene glycosides from sea cucumbers (Echinodermata, holothurioidea).

Abstract excerpt

Triterpene glycosides from sea cucumbers (Holothurioidea, Echinodermata) are used as a model for studying the biochemical evolution for correlation between the glycoside membranolytic activity and biological functions. Concepts of evolutionary morphology are applied at the molecular level. The concept of Van-der-Klaauve's- Dullemeijer's system-theoretical (holistic) approach is used for the model of...

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