XbaI polymorphism in the APOB gene and its association with increased cholesterol in children and adolescents: Ouro Preto study.

doi:10.1038/s41598-024-83099-8

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XbaI polymorphism in the APOB gene and its association with increased cholesterol in children and adolescents: Ouro Preto study.

Scientific reports - 28 Dec 2024

de Souza Thomás Viana, Batista Aline Priscila, de Menezes-Júnior Luiz Antônio Alves, Costa Anna Carolina Motta, Louzada Cibelle Ferreira, Lourenção Luciano Garcia, de Oliveira Wandeir Wagner, Lima Matheus Costa, Araujo Maisa Aparecida Marques, Baptista Izabela Vieira Duarte, de Souza Soares Ana Carolina, Guedes Raquel Laranjeira, Machado-Coelho George Luiz Lins

Abstract excerpt

Atherosclerotic vascular changes can begin during childhood, providing risk for cardiovascular disease (CVD) in adulthood. Identifiable risk factors such as dyslipidemia accelerate this process for some children. The apolipoprotein B (APOB) gene could help explain the inter-individual variability in lipid levels among young individuals and identify groups that require greater attention to prevent CVD. A...

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PMID: 39733208
DOI: 10.1038/s41598-024-83099-8
PMCID: PMC11682059

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