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SURVEY AND SUMMARY: Puralpha: a multifunctional single-stranded DNA- and RNA-binding protein

1 Sept 2000

Abstract excerpt

Puralpha is a ubiquitous, sequence-specific DNA- and RNA-binding protein which is highly conserved in eukaryotic cells. Puralpha has been implicated in diverse cellular functions, including transcriptional activation and repression, translation and cell growth. Moreover, this protein has been shown to be involved in regulating several human viruses which replicate in the central nervous system (CNS), including...

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PMID: 10954586
DOI: 10.1093/nar/28.17.3197

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