Article
Characterization of a variant of vga(A) conferring resistance to streptogramin A and related compounds.
Antimicrobial agents and chemotherapy - 1 Sept 2000
Haroche J, Allignet J, Buchrieser C, El Solh N
Abstract excerpt
A variant of the vga(A) gene (1,575 bp), encoding an ATP-binding cassette protein conferring resistance to streptogramin A and related antibiotics, was cloned from the chromosome of a Staphylococcus aureus clinical isolate and sequenced. The sequence of the variant was similar to that of the vga(A) gene (83.2% identity). However, the G+C content of the variant (35.6%) was higher than that of vga(A) (29%) and...
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