Article
Intraocular T cells of patients with herpes simplex virus (HSV)-induced acute retinal necrosis recognize HSV tegument proteins VP11/12 and VP13/14.
The Journal of infectious diseases - 1 Sept 2000
Verjans G M, Dings M E, McLauchlan J, van Der Kooi A, Hoogerhout P, Brugghe H F, Timmermans H A, Baarsma G S, Osterhaus A D
Abstract excerpt
It has previously been shown that T cells specific for the triggering virus infiltrate the eye of patients with herpes simplex virus type 1 (HSV-1)-induced acute retinal necrosis (ARN). The T cells were mainly directed against 0.67-0.73 HSV-1 map region encoded antigens. The fine specificities of genetically different T cell clones (TCC), obtained from affected eyes of 3 patients with HSV-induced ARN and reactive...
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