Article
The decapentaplegic morphogen gradient regulates the notal wingless expression through induction of pannier and u-shaped in Drosophila.
Mechanisms of development - 1 Aug 2000
Tomoyasu Y, Ueno N, Nakamura M
Abstract excerpt
The morphogen gradient of Wingless, a Wnt family member protein, provides positional information to cells in Drosophila imaginal discs. Elucidating the mechanism that precisely restricts the expression domain of wingless is important in understanding the two-dimensional patterning by secreted proteins in imaginal discs. In the pouch region of the wing disc, wingless is induced at the dorsal/ventral compartment...
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