Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of fucosyltransferases in the association between apomucin and Lewis antigen expression in normal and malignant gastric epithelium.

Gut - 1 Sept 2000

López-Ferrer A, de Bolós C, Barranco C, Garrido M, Isern J, Carlstedt I, Reis C A, Torrado J, Real F X

Abstract excerpt

BACKGROUND: In normal gastric epithelium, MUC5AC is detected in superficial epithelium associated with Lewis type 1 antigens and MUC6 is detected in antral glands with Lewis type 2. Therefore, the stomach constitutes an excellent model to examine the role of glycosyltransferases in determining the specificity of apomucin glycosylation. AIMS: To determine the molecular basis of this association and to examine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Tumor-Associated, Carbohydrate
Share to Fucosyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycosylation

Share to In Situ Hybridization

Share to Lewis X Antigen

Share to Neoplasm Proteins

Share to Stomach Neoplasms

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 10940270
DOI: 10.1136/gut.47.3.349
PMCID: PMC1728024

Genes

FUT1
FUT2
MUC2
MUC4
FUT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of fucosyltransferases in the association between apomucin and Lewis antigen expression in normal and malignant gastric epithelium.PMID 10940270Read ↗

Muc5ac gastric mucin glycosylation is shaped by FUT2 activity and functionally impacts Helicobacter pylori bindingSemantic proximity Read ↗

FUT11 Expression and Its Clinical Significance in Gastric CancerSemantic proximity Read ↗

Epithelial glycosylation in gut homeostasis and inflammation.Semantic proximity Read ↗

Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosaSemantic proximity Read ↗

Glycosyltransferases involved in type 1 chain and Lewis antigen biosynthesis exhibit glycan and core chain specificitySemantic proximity Read ↗

Role for α- l -fucosidase in the control of Helicobacter pylori -infected gastric cancer cellsSemantic proximity Read ↗

Lewis antigen alterations in a population at high risk of stomach cancer.Semantic proximity Read ↗

The Role of Sialyl-Tn in CancerSemantic proximity Read ↗

Regulation of glycosyltransferases and Lewis antigens expression by IL-1β and IL-6 in human gastric cancer cellsSemantic proximity Read ↗

Molecular mechanisms of Lewis antigen expression.Semantic proximity Read ↗

Lewis antigen expression and other pathogenic factors in the presence of atrophic chronic gastritis in a European population.Semantic proximity Read ↗

Infection by Helicobacter pylori expressing the BabA adhesin is influenced by the secretor phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.