Article
A new assay for the genetic study of general anesthesia in Drosophila melanogaster: use in analysis of mutations in the X-chromosomal 12E region.
Journal of neurogenetics - 1 Apr 2000
Guan Z, Scott R L, Nash H A
Abstract excerpt
We describe a new measure of the influence of general anesthetics on Drosophila that uses the robust tendency of fruit flies to briskly walk upwards after being tapped down. We expose flies to a fixed concentration of anesthetic gas in a 50 ml tube for a period of up to 1 h and then test the distribution of flies in the tube shortly after tapping them to its bottom. By measuring the effect of a series of...
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