Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic effects on an anesthetic-sensitive pathway in the brain of Drosophila.

Journal of neurobiology - 1 Jan 2000

Walcourt A, Nash H A

Abstract excerpt

General anesthetics are known to inhibit the electrically induced escape response of the fruitfly through action within the brain. We examined this response and its sensitivity to anesthetics in several mutants that cause significant disruption of the mushroom body and other structures of the central brain in adult flies. Because we show here that anesthesia sensitivity is influenced by genetic background, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anesthetics, Inhalation
Share to Brain
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escape Reaction

Share to Halothane

Share to Mutation

Share to Nerve Fibers

Share to Reaction Time

Source

Identifiers

PMID: 10623902

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic effects on an anesthetic-sensitive pathway in the brain of Drosophila.PMID 10623902Read ↗

A succession of anesthetic endpoints in the Drosophila brain.Semantic proximity Read ↗

Halothane presynaptically depresses synaptic transmission in wild-type Drosophila larvae but not in halothane-resistant (har) mutants.Semantic proximity Read ↗

Mutations that affect ion channels change the sensitivity of Drosophila melanogaster to volatile anesthetics.Semantic proximity Read ↗

A genetic and mosaic analysis of a locus involved in the anesthesia response of Drosophila melanogaster.Semantic proximity Read ↗

A genetic study of the anesthetic response: mutants of Drosophila melanogaster altered in sensitivity to halothane.Semantic proximity Read ↗

Physiology of mutations affecting learning and memory in Drosophila--the missing link between gene product and behavior.Semantic proximity Read ↗

New mutants of Drosophila that are resistant to the anesthetic effects of halothane.Semantic proximity Read ↗

Studies on target genes of general anesthetics.Semantic proximity Read ↗

Genetic effects in Drosophila on the potency of diverse general anesthetics: a distinctive pattern of altered sensitivity.Semantic proximity Read ↗

Use of Drosophila mutants to distinguish among volatile general anesthetics.Semantic proximity Read ↗

Blockage of one class of potassium channel alters the effectiveness of halothane in a brain circuit of Drosophila.Semantic proximity Read ↗

A kinder, gentler genetic analysis of behavior: dissection gives way to modulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.