Article
The alpha1-antichymotrypsin A-allele in German Parkinson disease patients.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 1999
Grasbon-Frodl E M, Egensperger R, Kösel S, Krüger R, Riess O, Mehraein P, Graeber M B
Abstract excerpt
An increased frequency of the A-allele of the alpha-antichymotrypsin (ACT) gene has been recently described in Japanese patients suffering from Parkinson disease (PD). In the present study, we have analyzed 62 German PD patients with regard to their ACT and APOE genotypes and compared them to 53 controls without clinical or pathological evidence of neurodegenerative disease. The A-allele frequency was 47% in PD...
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