Article
Sequence, organization, and evolution of Rh50 glycoprotein genes in nonhuman primates.
Journal of molecular evolution - 1 Jul 2000
Huang C H, Liu Z, Apoil P A, Blancher A
Abstract excerpt
The human RHAG locus encodes Rh50 glycoprotein, a polytopic protein that modulates expression of Rh antigens carried by Rh30 polypeptides. Rh50 is almost invariant, whereas Rh30 shows high polymorphism. To assess the relative conservation and phylogenetic relationship of RHAG genes, we characterized their protein expression, transcript structure, genomic organization, and noncoding regions (promoter and introns)...
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