Molecular insights into the Rh protein family and associated antigens.

Abstract excerpt

The Rh (Rhesus) protein family is expressed mainly in cells of erythroid lineage and, currently, is thought to comprise Rh30 (RhD and RhCE) polypeptides and Rh50 glycoprotein. As multipass integral membrane proteins, Rh30 and Rh50 are closely related by clear sequence homology and similar membrane topology, functioning respectively as the carrier and coexpressor of the Rh blood group antigens. The past year has...

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