Article
Molecular aspects of Rh antigens.
Legal medicine (Tokyo, Japan) - 1 Jul 2005
Iwamoto Sadahiko
Abstract excerpt
Since the cloning of two Rh related cDNAs, several attempts to clarify the molecular basis of Rh system have been performed. The RHD gene is deleted in most Caucasians who lack the D antigen, whereas some Japanese RhD(-) individuals appear to have an intact RHD gene. The expression study in erythroleukemic cells revealed that c and E antigens were expressed on a single polypeptide encoded by a full length cE...
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