Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myocilin and glaucoma: A TIGR by the tail?

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jul 2000

Johnson D H

Abstract excerpt

In 1997, Stone and 14 colleagues from 7 laboratories reported the identification of a gene (TIGR) associated with juvenile open-angle glaucoma (JOAG). Screening of adults with primary open-angle glaucoma (POAG) revealed that about 4% also carried a mutation of the coding region of this gene. The mutations were found through genetic linkage analysis of families with JOAG. Juvenile open-angle glaucoma was a logical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoskeletal Proteins
Share to DNA Mutational Analysis
Share to Eye Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Glaucoma, Open-Angle

Share to Glycoproteins

Share to Infant

Share to Trabecular Meshwork

Source

Identifiers

PMID: 10900113

Genes

MYOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myocilin and glaucoma: A TIGR by the tail?PMID 10900113Read ↗

The genetics of open-angle glaucoma: the story of GLC1A and myocilin.Semantic proximity Read ↗

Myocilin gene mutations: A cause of juvenile open-angle glaucoma in north IndiaSemantic proximity Read ↗

Prevalence of Mutations in TIGR/Myocilin in Patients with Adult and Juvenile Primary Open-Angle GlaucomaSemantic proximity Read ↗

Glaucoma genetics: where are we? Where will we go?Semantic proximity Read ↗

Analysis of glaucoma genes in Finnish patients with juvenile open-angle glaucoma.Semantic proximity Read ↗

The dawn of genetic testing for glaucoma.Semantic proximity Read ↗

Myocilin Mutation N480K Leads to Early Onset Juvenile and Adult-onset Primary Open Angle Glaucoma in a Six Generation Family.Semantic proximity Read ↗

Pro370Leu MYOC gene mutation in a large Chinese family with juvenile-onset open angle glaucoma: correlation between genotype and phenotype.Semantic proximity Read ↗

Mutations in the myocilin gene in families with primary open-angle glaucoma and juvenile open-angle glaucoma.Semantic proximity Read ↗

Analysis of MYOC gene mutation in a Chinese glaucoma family with primary open-angle glaucoma and primary congenital glaucoma.Semantic proximity Read ↗

New mutation in the myocilin gene segregates with juvenile-onset open-angle glaucoma in a Brazilian family.Semantic proximity Read ↗

Keeping an Eye on Myocilin: A Complex Molecule Associated with Primary Open-Angle Glaucoma SusceptibilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.