Article
Glaucoma genetics: where are we? Where will we go?
Current opinion in ophthalmology - 1 Apr 1999
Craig J E, Mackey D A
Abstract excerpt
The understanding of the genetic basis of the glaucomas has advanced rapidly. Mutations in the myocilin gene (previously known as TIGR) at the GLC1A locus on chromosome 1q21-q31 occur in a subset of patients with juvenile- and adult-onset primary open-angle glaucoma. Five other genetic localizations for primary open-angle glaucoma have now been reported. In patients with primary congenital glaucoma, mutations...
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