Article
Antiretroviral therapy. Sequencing antiretrovirals.
The AIDS reader - 1 Jun 2000
MacArthur R D
Abstract excerpt
Sequencing of antiretroviral agents is of interest because the majority of HIV-infected individuals in clinical practice experience virologic rebound after 1 to 2 years of therapy. Sequencing strategies are based on the observation that different mutational patterns arise after exposure to particular antiretroviral agents within the same class and on preliminary data suggesting that not all mutations impart the...
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