Article
[Hereditary cancer syndromes: a modern paradigm].
Problemy endokrinologii - 1 Sept 2020
Baranova Elena E, Bodunova Natalia A, Vorontsova Мaria V, Zakharova Galina S, Makarova Maria V, Rumyantsev Pavel O, Hat'kov Igor E
Abstract excerpt
About 5-10% of malignant neoplasms (MN) are hereditary. Carriers of mutations associated with hereditary tumor syndromes (HTS) are at high risk of developing tumors in childhood and young age and synchronous and metachronous multiple tumors. At the same time, this group of diseases remains mainly an oncological problem, and clinical decisions are made only when MNs are detected in carriers of pathogenic...
Topics
- Genetic Counseling
- Genetic Testing
- Heterozygote
- Humans
- Mutation
- Neoplastic Syndromes, Hereditary