Article
Do escape mutants explain rapid increases in dengue case-fatality rates within epidemics?
Lancet (London, England) - 27 May 2000
Guzmán M G, Kourí G, Halstead S B
Abstract excerpt
During the Cuban dengue epidemics of 1981 and 1997, significant monthly increases were observed in the proportion of total cases that presented as dengue haemorrhagic fever or dengue shock syndrome (DHF/DSS), and in case-fatality rates for both dengue fever and DHF/DSS. We believe that theses increases can be explained by the hypothesis that some of the population of antibodies against dengue 1 virus raised after...
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