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Recovery of Pathogenic Measles Virus from Cloned cDNA

15 Jul 2000

Abstract excerpt

Reverse genetics technology so far established for measles virus (MeV) is based on the Edmonston strain, which was isolated several decades ago, has been passaged in nonlymphoid cell lines, and is no longer pathogenic in monkey models. On the other hand, MeVs isolated and passaged in the Epstein-Barr virus-transformed marmoset B-lymphoblastoid cell line B95a would retain their original pathogenicity (F. Kobune et...

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Identifiers

PMID: 10864679
DOI: 10.1128/jvi.74.14.6643-6647.2000

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