Article
Response of pre-core mutant chronic hepatitis B infection to lamivudine.
Journal of medical virology - 1 Jul 2000
Rizzetto M, Volpes R, Smedile A
Abstract excerpt
The proportion of chronic liver disease associated with the pre-core mutant of hepatitis B virus (HBV) infection is increasing, particularly in Mediterranean Europe and in Asia. The pre-core mutant HBV is unable to produce hepatitis B e antigen (HBeAg), so that patients with this variant do not present with HBV characterised by HBeAg in the serum. Pre-core mutant chronic hepatitis B infection usually proceeds to...
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