Article
Current pharmacotherapy for the treatment of chronic hepatitis B.
Expert opinion on pharmacotherapy - 1 Oct 2003
Lagget M, Rizzetto M
Abstract excerpt
The virological profile of infection with the hepatitis B virus (HBV) is changing in many parts of the world from the classical hepatitis B e antigen (HBeAg)-positive serological pattern to a HBeAg-negative pattern, linked to the replacement of wild-type HBV by HBV variants with mutations in the core-promoter and in the precore region that prevent the secretion of HBeAg. The wild-type HBV disease is characterised...
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