Article
Derivation of the relationship between neutral mutation and fixation solely from the definition of selective neutrality.
Proceedings of the National Academy of Sciences of the United States of America - 20 Jun 2000
Tomizawa J
Abstract excerpt
A mutation whose fixation is independent of natural selection is termed a neutral mutation. Therefore selective neutrality of a mutation can be defined by independence of its fixation from natural selection. By the population genetic approach, Kimura [Kimura, M. (1962) Genetics 47, 713-719] predicted that the probability of fixation of a neutral mutation (u) is equal to the frequency of the new allele at the...
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