Article
Biological basis of radiation sensitivity. Part 2: Cellular and molecular determinants of radiosensitivity.
Oncology (Williston Park, N.Y.) - 1 May 2000
Rosen E M, Fan S, Goldberg I D, Rockwell S
Abstract excerpt
Recent studies have elucidated some of the molecular and cellular mechanisms that determine the sensitivity or resistance to ionizing radiation. These findings ultimately may be useful in devising new strategies to improve the therapeutic ratio in cancer treatment. Despite the rapid advances in knowledge of cellular functions that affect radiosensitivity, we still cannot account for most of the clinically...
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