Article
Cellular, molecular, and carcinogenic effects of radiation.
Hematology/oncology clinics of North America - 1 Apr 1993
Little J B
Abstract excerpt
(1) The biologic effects of ionizing radiation at the cellular and molecular levels differ from those of many chemical agents. Radiation is a classic genotoxic agent. The important DNA lesion with respect to its cytotoxic and mutagenic effects appears to be the DNA double strand break, whereas chemotherapeutic alkylating agents induce primarily base damage from adduct formation and cross-linking....
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