Article
Vibrio vulnificus has the transmembrane transcription activator ToxRS stimulating the expression of the hemolysin gene vvhA.
Journal of bacteriology - 1 Jun 2000
Lee S E, Shin S H, Kim S Y, Kim Y R, Shin D H, Chung S S, Lee Z H, Lee J Y, Jeong K C, Choi S H, Rhee J H
Abstract excerpt
In an attempt to dissect the virulence regulatory mechanism in Vibrio vulnificus, we tried to identify the V. cholerae transmembrane virulence regulator toxRS (toxRS(Vc)) homologs in V. vulnificus. By comparing the sequences of toxRS of V. cholerae and V. parahaemolyticus (toxRS(Vp)), we designed a degenerate primer set targeting well-conserved sequences. Using the PCR product as an authentic probe for Southern...
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