Article
Alpha integrin subunits regulate human (Caco-2) intestinal epithelial proliferation and phenotype.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2000
Basson M D, Emenaker N J, Sanders M A
Abstract excerpt
BACKGROUND/AIMS: Cell-matrix interactions influence intestinal epithelial biology, but the whether specific integrin heterodimers exert different effects is unclear. METHODS: We used functional antibodies to investigate effects of the alpha2, alpha3, alpha5, and alpha6 integrin subunits on proliferation and differentiation of human intestinal Caco-2 cells on laminin. Cells seeded onto laminin-coated inserts in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
