Article
Methods for estimating gene frequencies and detecting selection in bacterial populations.
Genetics - 1 Jun 2000
Rannala B, Qiu W G, Dykhuizen D E
Abstract excerpt
Recent breakthroughs in molecular technology, most significantly the polymerase chain reaction (PCR) and in situ hybridization, have allowed the detection of genetic variation in bacterial communities without prior cultivation. These methods often produce data in the form of the presence or absence of alleles or genotypes, however, rather than counts of alleles. Using relative allele frequencies from...
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