Potential mechanisms of mutations that affect neuronal migration in man and mouse.

Abstract excerpt

Mutations in the genes that encode filamin-1, Lis1 and doublecortin are responsible for X-linked lissencephaly in man, whereas mutations in the genes that encode Cdk5, its activator p35 and the reelin-signaling pathway disturb migration and architectonic development in mice. To understand the action of genes that control neuronal migration and the phenotype of corresponding defects, it might be as important to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to 1-Alkyl-2-acetylglycerophosphocholine Esterase
• Share to Congenital Abnormalities