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MHC class I and class II phenotype, gene, and haplotype frequencies in Greeks using molecular typing data.

Human immunology - 1 Jun 2000

Papassavas E C, Spyropoulou-Vlachou M, Papassavas A C, Schipper R F, Doxiadis I N, Stavropoulos-Giokas C

Abstract excerpt

In the present study, DNA typing for HLA-A, C, B, DRB1, DRB3, DRB4, DRB5, DQA1, DQB1, and DPB1 was performed for 246 healthy, unrelated Greek volunteers of 20-59 years of age. Phenotype, genotype frequencies, Hardy-Weinberg equilibrium fit, and 3-locus haplotype frequencies for HLA-A, C, B, HLA-A, B, DRB1, HLA-DRB1, DQA1, DQB1, and HLA-DRB1, DQB1, DPB1 were calculated. Furthermore, linkage disequilibrium, deltas,...

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PMID: 10825590
DOI: 10.1016/s0198-8859(00)00115-4

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