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Characterization of the 1918 “Spanish” influenza virus neuraminidase gene

23 May 2000

Abstract excerpt

The "Spanish" influenza pandemic of 1918 was characterized by exceptionally high mortality, especially among young adults. The surface proteins of influenza viruses, hemagglutinin and neuraminidase, play important roles in virulence, host specificity, and the human immune response. The complete coding sequence of hemagglutinin was reported last year. This laboratory has now determined the complete coding sequence...

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PMID: 10823895
DOI: 10.1073/pnas.100140097

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