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Initial Genetic Characterization of the 1918 “Spanish” Influenza Virus

21 Mar 1997

Abstract excerpt

The "Spanish" influenza pandemic killed at least 20 million people in 1918-1919, making it the worst infectious pandemic in history. Understanding the origins of the 1918 virus and the basis for its exceptional virulence may aid in the prediction of future influenza pandemics. RNA from a victim of the 1918 pandemic was isolated from a formalin-fixed, paraffin-embedded, lung tissue sample. Nine fragments of viral...

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PMID: 9065404
DOI: 10.1126/science.275.5307.1793

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