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Article

Metalloprotease is not essential for Vibrio vulnificus virulence in mice.

Infection and immunity - 1 Jun 2000

Shao C P, Hor L I

Abstract excerpt

Previous work suggested that a metalloprotease, Vvp, may be a virulence factor of Vibrio vulnificus, which causes severe wound infection and septicemia in humans. To determine the role of Vvp in pathogenesis, we isolated an isogenic protease-deficient (PD) mutant of Vibrio vulnificus by in vivo allelic exchange. This PD mutant was as virulent as its parental strain in mice infected intraperitoneally and was...

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Identifiers

PMID: 10816513
DOI: 10.1128/IAI.68.6.3569-3573.2000
PMCID: PMC97644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Metalloprotease is not essential for Vibrio vulnificus virulence in mice.PMID 10816513Read ↗

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