Article
Vibrio vulnificus metalloprotease VvpE has no direct effect on iron-uptake from human hemoglobin.
Journal of microbiology (Seoul, Korea) - 1 Oct 2006
Sun Hui-Yu, Han Song-Iy, Choi Mi-Hwa, Kim Seong-Jung, Kim Choon-Mee, Shin Sung-Heui
Abstract excerpt
This study was designed to determine whether or not Vibrio vulnificus metalloprotease VvpE can promote iron uptake via the proteolytic cleavage of human hemoglobin. We found that V. vulnificus utilized hemoglobin as an iron source more efficiently via the vulnibactin-mediated iron-uptake system than via the HupA-mediated iron-uptake system and, of the proteases produced by V. vulnificus, VvpE was found to be the...
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