Article
Hyperinsulinism of the newborn.
Seminars in perinatology - 1 Apr 2000
Glaser B
Abstract excerpt
Neonatal hyperinsulinism (HI) is a clinical syndrome of pancreatic beta-cell dysfunction characterized by failure to suppress insulin secretion in the presence of hypoglycemia. Although rare, it is the most common cause for persistent hypoglycemia in the newborn period. Treatment can be extremely difficult, and partial pancreatectomy is frequently required to prevent recurrent hypoglycemia and irreversible brain...
Topics
- Glucokinase
- Glutamate Dehydrogenase
- Humans
- Hyperinsulinism
- Infant, Newborn
- Mutation
- Potassium Channels