Article
Hyperinsulinism in infancy: understanding the pathophysiology.
The international journal of biochemistry & cell biology - 1 Sept 2003
Hussain K, Aynsley-Green A
Abstract excerpt
Hyperinsulinism in infancy (HI) is the commonest cause of persistent and recurrent hypoglycaemia in the infancy and childhood period. HI is a heterogeneous disorder with respect to clinical presentation, histology, molecular biology and genetics. Recent advances have provided unique insights into the pathophysiology of this intriguing disease as well as providing an understanding of the normal physiological and...
Topics
- 3-Hydroxyacyl CoA Dehydrogenases
- ATP-Binding Cassette Transporters
- Blood Glucose
- Glucokinase
- Humans
- Hyperinsulinism
- Hypoglycemia
- Infant
- Infant, Newborn
- Mutation
- Potassium Channels